Drugs That Should Be Avoided For G6PD Deficient
Analgesics / Antipyretics:
- Anacin
- Aspirin
- Paracetamol (acetaminophen)
- Bufferin
- Dipirona
- Ecotrin
- Empirin
- Excedrin
- Pepto Bismol
- Phenacetin (acetophenetidin)
- Probenecid
Antihistamine:
- Azatadine
- Brofeniramine
- Dexchlorphyrramine
- Diphenhydramine
- Hydroxyzine
- Loratadine
- Cetirizine
Antimalarials:
- Chloroquine (Aralen)
- Mefloquine (Lariam)
- Pamaquine
- Pentaquine
- Primaquine
- Quinidine
- Quinine
Sulfonamides and Sulfones:
- Dapsone
- Furosemide (Lasix)
- Sulfacetamide (Sulamyd)
- Sulfamethoxazole (Bactrim, Septra)
- Sulfanilamide
- Sulfasalazine (Azulfidine)
- Sulfisoxazole (Gantrisin)
- Sulfamethoxypyridazine
Cytotoxic / Antibacterial:
- Nalidixic Acid
- Para-Aminosalicylic Acid
- Chloramphenicol
- Co-Trimoxazole
- Furazolidone
- Furmetonol
- Neoarsphenamine
- Streptomycin
Nitrofurans:
- Nitrofurantoin (Furadantin, Macrobid, Macrodantin)
- Nitrofurazone (Furacin)
Quinolones and Fluoroquinolones:
- Ciprofloxacin (Cipro)
- Levofloxacin (Levaquin)
- Moxifloxacin (Avelox, Vigamox)
- Norfloxacin (Noroxin)
Cardiovascular Drugs:
- Captopril
- Hydralazine
- Procainamide
- Quinidine
- Enalapril
MISCELLANEOUS:
- Acetylsalicylic Acid (ASA, Mejoral)
- Ascorbic Acid (Vitamin C)
- Para-Aminobenzoic Acid (Complex B10)
- Tonic water
- Alpha Methyldopa
- Aminopyrine
- Antazoline
- Methylene Blue (used in contrast)
- Toluidine blue (used in contrast)
- Bupivacaine (anesthesia)
- Colchicine
- Artificial Dyes
- Diphenhydramine (Anador, Caladryl)
- Dimercaprol
- Fava beans
- Phenylbutazone
- Phenytoin (Hydantal)
- Glibenclamide
- Isoniazid
- L-Dopa
- Mestranol
- Naphthalene
- Niridazole
- Piridium
- Pyrimethamine
- Sulfacillin
- Sulfadiazine
- Sulfaguanidine
- Sulfamerazine
- Sulfamethoxypyridazine
- Trimetropim (Bactrim)
- Trinitrotoluene
- Tripelenamine
- Urato Oxidase
- Red wine
- Vitamin K (Kanakion)
- Acetylphenylhydrazine
- Beta-Naphthol
- Chloramphenicol
- Dimercaprol
- Glyburide (Diabeta)
- Henna
- Menthol
- Penicillamine
- Phenazopyridine
- Phenylhydrazine
- Rasburicase (Elitek)
- Tolbutamide (Orinase)
SOURCE:
PEDIATRIC HEMATOLOGY DEPARTMENT OF THE SCHOOL PAULISTA DE MEDICINA. RESEARCHERS DR.SERGIO AUGUSTO PERLAMAGNA (CRM: 99243)
Cappellini MD, Fiorelli G. Glucose-6-phosphate dehydrogenase deficiency. Lancet. 2008;371(9606):64–74
Minucci A, Moradkhani K, Hwang MJ, et al. Glucose-6-phosphate dehydrogenase (G6PD) mutations database: review of the ‘old’ and update of the new mutations. Blood Cells Mol Dis. 2012;48(3):154–165.
The Association is affiliated with UNIAMO, Italian Federation for Rare Diseases, which is member of EURORDIS, European Organization for Rare Diseases.